The Download: experimental embryos and the US monkeypox emergency

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In a search for novel forms of longevity medicine, a biotech company based in Israel says it intends to create embryo-stage versions of people in order to harvest tissues for use in transplant treatments.

The company, Renewal Bio, is pursuing recent advances in stem-cell technology and artificial wombs, demonstrated by Jacob Hanna, a biologist at the Weizmann Institute of Science in Rehovot. Earlier this week, Hanna showed that starting with mouse stem cells, his lab could form highly realistic-looking mouse embryos and keep them growing in a mechanical womb for several days until they developed beating hearts, flowing blood, and cranial folds. 

It’s the first time such an advanced embryo has been mimicked without sperm, eggs, or even a uterus. Now Hanna has set his sights on extending the technology to humans—he’s already experimenting with human cells and hopes to eventually produce artificial models of human embryos. “We view the embryo as the best 3D bio printer,” he says. Read the full story.

—Antonio Regalado

Automated techniques could make it easier to develop AI

Machine-learning researchers have to make many decisions when designing new models, meaning that complex models end up being designed by human intuition, rather than systematically. A growing field called automated machine learning, or autoML, aims to eliminate that guesswork, allowing algorithms to take over the decision making, which could both simplify the process and make machine learning more accessible.

Big Tech is paying attention. Companies like Amazon and Google already offer low-code machine-learning tools that take advantage of autoML techniques, and computer scientists are excited by the notion of being able to simply specify a problem, before tasking the computer with figuring it out. But researchers have a lot of work to do before autoML can be deployed more widely. Read th...

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