SINGAPORE – Ms Michelle Mak used to be hypersensitive to the cold. For most of her life, she hated rainy days, cool weather and air-conditioning. Dips in the external temperature set off fevers, rashes all over her body and joint stiffness.

“I would wear two pairs of pants, three shirts and a jacket and still feel discomfort,” recalls Ms Mak, who turns 46 in 2025.

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